Fig 2. (A) Serum concentrations (ng/ml) of anti-ROR1 antibodies (ELISA) against a full length ROR1 protein and (B) a ROR1 KNG protein in CLL patients (n = 23): (●) non-progressive (n = 15) and (x) progressive (n = 8) CLL patients and (○) control donors (n = 20). Dotted line represents mean+2SD of controls. ***p<0.0001. (C) Reactivity of sera from CLL patients with a recombinant CEA protein. The results are shown as OD values at 450 nm for 1:50 and 1:100 serum dilutions. (D) Relation between conc. of antibodies against a full length ROR1 protein and ROR1 KNG protein in 23 CLL patients.