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. Author manuscript; available in PMC: 2016 Jun 10.
Published in final edited form as: Cell Host Microbe. 2015 Jun 10;17(6):775–787. doi: 10.1016/j.chom.2015.05.011

Figure 7. Model Depicting Multi-Cellular Targeting of S. aureus Hla in Sepsis.

Figure 7

(A) S. aureus α-toxin contributes to temporospatial lung and liver injury by preventing adequate platelet repair and exacerbating the host inflammatory response.

(B) Consequences of selective deletion of ADAM10 on platelets or myeloid lineage cells.