Table 1.

Planned dosing cohorts

Cohort	Carfilzomib,* mg/m2	Pomalidomide, mg	Dexamethasone,† mg
−3	20	2	40
−2	27	2	40
−1	27	3	40
1 (initial dose level)	27	4	40
2	36	4	40
3	45	4	40
4	56	4	40

Carfilzomib was administered IV over 30 minutes; pomalidomide was administered orally; dexamethasone was administered either IV or orally.

^*The first 2 doses of carfilzomib in cycle 1 were to be administered at 20 mg/m².

^†Dosing of dexamethasone may be modified at the discretion of the treating investigator.