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Feedback circuit model of appetitive LTM formation. Neuronal signal of a sugar reward mediated by PAM-α1 converges with olfactory information in the α/β KCs. The coincidental signal is read out through MBON-α1 to give glutamatergic feedback onto PAM-α1 for the gain control of the dopamine release. Appetitive LTM is read out through MBON-α1 to activate other downstream targets.
