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BRAF inhibition leads to an up regulation of MITF in primary melanoma cell lines. (A) Western blot analysis of MITF protein in primary cell lines Mel-V, Mel-2, KFM, and GLM-2 treated with 5μM and 10μM PLX4032 for 24 hours. (B) Densitometric representation of Figure A expressed as percent change from untreated control by Western Blot analysis.
