Table 3.
Most common potentially inappropriate prescriptions
| Criterion | n (%) | n (%) causing ADRs |
|---|---|---|
| Aspirin with no history of coronary, cerebral or peripheral arterial symptoms or occlusive arterial event | 154 (18.9) | 7 (6.5) |
| Benzodiazepines in those prone to fall | 43 (5.4) | 10 (23.3) |
| NSAID with moderate-severe hypertension | 41 (5.0) | 1 (2.4) |
| Long-term long-acting benzodiazepines | 37 (4.6) | 3 (8.1) |
| Prolonged use (>1 week) of first generation antihistamines | 28 (3.4) | 7 (25.0) |
| Use of long-term powerful opiates as first-line therapy for mild-moderate pain | 27 (3.3) | 0 (0) |
| Long-term opiates in those with recurrent falls | 26 (3.2) | 6 (23.1) |
| Long-term (i.e. >1 month) neuroleptics as long-term hypnotics | 26 (3.2) | 12 (46.2) |
| Oestrogens without progestogen in patients with intact uterus | 23 (2.8) | 0 (0) |
| Long-term corticosteroids (>3 months) as monotherapy for rheumatoid arthritis or osteoarthritis | 19 (2.3) | 2 (10.5) |
| Aspirin at dose >150 mg/day | 17 (2.1) | 0 |
| Long-term use of NSAID (>3 months) for relief of mild joint pain in osteoarthritis | 14 (1.7) | 0 |
| Vasodilator drugs known to cause hypotension in those with persistent postural hypotension | 13 (1.6) | 12 (92.3) |
| Systemic corticosteroids instead of inhaled corticosteroids for maintenance therapy in moderate–severe COPD | 12 (1.5) | 0 |
| First-generation antihistamines in those prone to fall | 11 (1.4) | 1 (9.1) |
| Neuroleptic drugs in those prone to fall | 10 (1.2) | 0 |
| Total | 607 PIPs (374 persons) | 64 (10.5) |
ADR adverse drug reaction, NSAID non-steroidal anti-inflammatory drugs, COPD chronic obstructive pulmonary disease