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. 2015 Sep 26;71(12):1525–1533. doi: 10.1007/s00228-015-1950-8

Table 3.

Most common potentially inappropriate prescriptions

Criterion n (%) n (%) causing ADRs
Aspirin with no history of coronary, cerebral or peripheral arterial symptoms or occlusive arterial event 154 (18.9) 7 (6.5)
Benzodiazepines in those prone to fall 43 (5.4) 10 (23.3)
NSAID with moderate-severe hypertension 41 (5.0) 1 (2.4)
Long-term long-acting benzodiazepines 37 (4.6) 3 (8.1)
Prolonged use (>1 week) of first generation antihistamines 28 (3.4) 7 (25.0)
Use of long-term powerful opiates as first-line therapy for mild-moderate pain 27 (3.3) 0 (0)
Long-term opiates in those with recurrent falls 26 (3.2) 6 (23.1)
Long-term (i.e. >1 month) neuroleptics as long-term hypnotics 26 (3.2) 12 (46.2)
Oestrogens without progestogen in patients with intact uterus 23 (2.8) 0 (0)
Long-term corticosteroids (>3 months) as monotherapy for rheumatoid arthritis or osteoarthritis 19 (2.3) 2 (10.5)
Aspirin at dose >150 mg/day 17 (2.1) 0
Long-term use of NSAID (>3 months) for relief of mild joint pain in osteoarthritis 14 (1.7) 0
Vasodilator drugs known to cause hypotension in those with persistent postural hypotension 13 (1.6) 12 (92.3)
Systemic corticosteroids instead of inhaled corticosteroids for maintenance therapy in moderate–severe COPD 12 (1.5) 0
First-generation antihistamines in those prone to fall 11 (1.4) 1 (9.1)
Neuroleptic drugs in those prone to fall 10 (1.2) 0
Total 607 PIPs (374 persons) 64 (10.5)

ADR adverse drug reaction, NSAID non-steroidal anti-inflammatory drugs, COPD chronic obstructive pulmonary disease