Table 3.
Genotype and allele distribution of C(-1562)T gene polymorphism in MMP-9 gene in stroke patients with and without T2DM
| N | Genotypes | Alleles | OR (95 % CI) | |||||
|---|---|---|---|---|---|---|---|---|
| CC | CT | TT | CT + TT | C | T | CT + TT genotype | T allele | |
| STR + T2DM | ||||||||
| 169 | 84 (50) | 72 (43) | 13 (7) | 85 (50) | 0.71 | 0.29 | 1.44 (1.93–2.24) p = 0.101 |
1.48 (1.03–2.12) p = 0.031 |
| STR no T2DM | ||||||||
| 153 | 90 (59) | 60 (39) | 3 (2) | 63 (41) | 0.78 | 0.22 | Ref. | Ref. |
| Controls | ||||||||
| 410 | 283 (69) | 119 (29) | 8 (2) | 127 (31) | 0.84 | 0.16 | ||
Genotype distribution is shown as numbers (%). For STR + T2DM subgroup compared with control group, OR is 2.07 (95 % CI 1.53–2.79) for T allele and 2.25 (95 % CI 1.56–3.25) for CT + TT genotype
STR stroke, T2DM type 2 diabetes