Figure 5.

Caloric restriction prevented age-dependent long-term memory deterioration. (A) Average errors corrected over six blocks of the control mice, with significant cognitive difference observed on Blocks 3 and 4. (B) Average errors corrected over six blocks of the CR mice, with significant cognitive difference observed on Block 3. (C) Comparison of the errors made by the four groups on Block 3, an index of learning ability and short-term memory. (D) Comparison of the errors made by the four groups on Block 4, and index of long-term memory. Data are presented as Mean ± SEM. *p < 0.05; **p < 0.01.