Table 2.

Kinetic data and isobaric activation parameters at 298 K for the Diels–Alder reactions^[a]

	d⋅Cu2+	CB[8]⋅d⋅Cu2+	e⋅Cu2+	CB[8]⋅e⋅Cu2+
kapp (mol s−1)	0.022	0.089	0.050	0.48
Keq(m−1)	1.77×103	2.07×104	2.31×103	1.91×104
kcat (mol s−1)	0.252	0.184	0.451	1.04
ΔG≠(kcal mol−1)	19.7	18.9	19.2	17.9
ΔH≠(kcal mol−1)	4.4	7.2	2.6	5.3
TΔS≠(kcal mol−1)	−15.3	−11.7	−16.6	−12.6

[a] Fixed ratio of amino acids to Cu²⁺ 1.5:1. In the presence of CB[8], CB[8]:d/e:Cu²⁺=2:1.5:1.