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. 2015 Nov 13;35(6):e00265. doi: 10.1042/BSR20150188

Table 3. Xenograft mouse or rat tumours, Route: IV, IP, IT.

Abbreviations: AlOH-PC, hydroxyaluminum-phthalocyanine; BPD-MA, benzoporphyrin derivative monoacid ring A; CD1, a strain of mice; DLI, drug light interval; Ncr, another strain of mice; NSCLC, non small cell lung cancer; Pd, TOOKAD, palladium bacteriopheophorbide; sc, subcutaneous; SCC, squamous cell carcinoma.

Cell line Cancer type Animal model PDT regimen References
OVCAR3 Ovarian Nude mice Photofrin, DLI 24 h, 635 nm, 200 J/cm2 [63]
OVCAR5 Ovarian Nude mice Verteporfin, BPD-MA, DLI 90 min, 690 nm, 40 J, 320 s [64]
AsPC-1 andPanc-1 Pancreas Male SCID mice Verteporfin, DLI 1 h, 690 nm, 40 J/cm2, 74mW/cm2 [65]
LNCaP Prostate SCID mice Liposomal BPD, DLI 1 h, 690 nm,100 J/cm2 [66]
WISH-PC237 Prostate Male CD1 nude mice Pd-bacteriopheophorbide TOOKAD, DLI zero, 650–800 nm, 360 J/cm2, 30 min [67]
Eca109 Oesophageal SCC Nude mice (sc or orthotopic) Photofrin, DLI 24 h, 630 nm, 135 J/cm2, 75 mW/cm2 [68]
A549 Lung cancer (NSCLC) nude mice Factor VII-targeted Sn(IV) chlorin e6 conjugate, 635 nm, 72 J/cm2 [69]
H460 Lung cancer (NSCLC) Ncr-nu/nu female mice Photochlor HPPH, DLI 24 h, 661 nm, 200 J/cm. 150 mW/cm [70]
FaDu Head and neck SCC Female nu/nu CByJ.Cg-Foxn1nu/J. HPPH, DLI 24 h, 665 nm, 48 Jcm2, 7 mW/cm2, [52]
MDA-MB 231 Mammary carcinoma Nude mice Phthalocyanine, AlOH-PC, DLI 10 min, 635 nm, 100 J/cm2, 0.97 W, 7 min. [71]
MCaIV Breast Female SCID Pyropheophorbide MV6401, DLI 15 min, 664 nm, 5 J/cm2, 50 mW/cm2. [72]
HT29 Liver Female Swiss nude mice Monoclonal antibody chlorin(e6) conjugate, 17.1A-pl-ce6-succ, DLI 3 h, 666 nm, 80 J, 100 mW, 13.3 min [73]
NPC Nasopharyngeal carcinoma BALB/c nude mice 5-ALA, DLI 3.5 h, 630 nm, 100 J/cm2, 100 mW/cm2 [74]