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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Psychosom Med. 2015 Nov-Dec;77(9):969–981. doi: 10.1097/PSY.0000000000000247

Figure 4.

Figure 4

Correlation between depression and alpha diversity in samples from patients with AN at hospital admission (T1). Bacterial composition was characterized by 454 pyrosequencing of the 16S rRNA gene, and sequencing results were processed by the Quantitative Insights Into Microbial Ecology (QIIME) pipeline. Richness (vertical axes) was characterized by the (A) number of observed bacterial species in each sample and (B) Chao-1 estimator of diversity. AN patients (n=15; one patient did not complete the surveys) completed the Beck Depression Inventory-II (horizontal axes) within 24 hours of admission. Associations between T1 psychopathology scores and alpha diversity were examined with the tau-b correlation coefficient. Depression was negatively associated with the number of observed bacterial species (p=0.026) and Chao-1 estimator (p=0.026).