Table 5.
Hospital admission (T1): microbial taxa and diversity measures associated with eating disorder psychopathology in females with AN (n=15)
| Taxonomic/diversity level |
Classification | Behavioral measure |
Test statistic |
p | FDR corrected p |
|---|---|---|---|---|---|
| Order | Actinomycetales | ShapeC | 0.450 | 0.024 | 0.40 |
| WeightC | 0.434 | 0.030 | 0.40 | ||
| Clostridiales | EatingC | −0.452 | 0.020 | 0.40 | |
| EDEQ | −0.448 | 0.020 | 0.40 | ||
| Turicibacterales | EatingC | −0.484 | 0.018 | 0.40 | |
| Family | Actinomycetaceae | ShapeC | 0.450 | 0.024 | 0.34 |
| WeightC | 0.434 | 0.030 | 0.38 | ||
| Clostridiaceae | Restraint | −0.437 | 0.025 | 0.34 | |
| Clostridiales_family | WeightC | −0.453 | 0.022 | 0.34 | |
| Odoribacteraceae | Restraint | 0.450 | 0.024 | 0.34 | |
| Ruminococcaceae | Restraint | −0.554 | 0.005 | 0.16 | |
| EatingC | −0.529 | 0.006 | 0.16 | ||
| ShapeC | −0.534 | 0.006 | 0.16 | ||
| WeightC | −0.579 | 0.003 | 0.16 | ||
| EDEQ | −0.600 | 0.002 | 0.16 | ||
| Turicibacteraceae | EatingC | −0.484 | 0.018 | 0.34 | |
| Genus | Anaerostipes | EatingC | −0.463 | 0.028 | 0.47 |
| ShapeC | −0.491 | 0.021 | 0.47 | ||
| WeightC | −0.508 | 0.017 | 0.47 | ||
| EDEQ | −0.505 | 0.016 | 0.47 | ||
| Bacteroidaceae_genus | EatingC | 0.449 | 0.030 | 0.47 | |
| Clostridiales_genus | WeightC | −0.453 | 0.022 | 0.47 | |
| Clostridium | EatingC | −0.445 | 0.037 | 0.47 | |
| Eubacteriaceae_genus | ShapeC | −0.431 | 0.042 | 0.47 | |
| Faecalibacterium | EatingC | −0.425 | 0.029 | 0.47 | |
| ShapeC | −0.459 | 0.019 | 0.47 | ||
| WeightC | −0.394 | 0.046 | 0.47 | ||
| EDEQ | −0.383 | 0.047 | 0.47 | ||
| Lachnospira | ShapeC | −0.510 | 0.011 | 0.47 | |
| WeightC | −0.495 | 0.015 | 0.47 | ||
| EDEQ | −0.411 | 0.038 | 0.47 | ||
| Ruminococcaceae_genus | EatingC | −0.433 | 0.026 | 0.47 | |
| ShapeC | −0.418 | 0.032 | 0.47 | ||
| WeightC | −0.422 | 0.032 | 0.47 | ||
| TotalC | −0.429 | 0.026 | 0.47 | ||
| Ruminococcus | EDEQ | −0.390 | 0.042 | 0.47 | |
| Turicibacter | EatingC | −0.484 | 0.018 | 0.47 | |
| Veillonella | WeightC | −0.512 | 0.020 | 0.47 | |
| Alpha diversity | # of observed species | ShapeC | −0.515 | 0.008 | 0.045 |
| WeightC | −0.441 | 0.025 | 0.045 | ||
| EDEQ | −0.429 | 0.026 | 0.045 | ||
| Chao-1 estimator | ShapeC | −0.476 | 0.015 | 0.090 | |
| Beta diversity | Weighted (PC 4) | EatingC | −0.394 | 0.042 | 0.83 |
| Unweighted (PC 1) | EatingC | −0.413 | 0.033 | 0.58 | |
| ShapeC | −0.437 | 0.025 | 0.58 | ||
| WeightC | −0.422 | 0.032 | 0.58 | ||
| EDEQ | −0.448 | 0.020 | 0.58 | ||
FDR = false discovery rate; PC = principal coordinate
EDEQ refers to the total score on the Eating Disorder Examination-Questionnaire. The following subscales are also included: Dietary Restraint (Restraint), Eating Concern (EatingC), Shape Concern (ShapeC), Weight Concern (WeightC)
Alpha = 0.05; FDR level = 0.1
Associations were examined with the tau-b correlation coefficient.