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. Author manuscript; available in PMC: 2016 Nov 9.
Published in final edited form as: Dev Cell. 2015 Nov 9;35(3):281–294. doi: 10.1016/j.devcel.2015.10.007

Figure 6. WASP/Myosin complex functions as a single protein with only four activities.

Figure 6

(A) Model: The WASP/Myosin complex has four activities that are necessary for CME and sufficient for a functional WASP/Myosin complex.

(B) Theoretical outward-directed movement of individual, growing actin filaments that are tethered to the bud tip but not the base.

(C) Model: The TH1 and motor domains constitute a membrane-actin linkage that tethers F-actin to the base of endocytic sites. While the F-actin at endocytic sites is a branched, cross-linked network, we have shown only two individual filaments for clarity of presentation. See also Movie S5.