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Top: linear regression analyses of percent methylation at variable sites in AKR7A2 versus cardiac AKR7A2 mRNA expression. Each circle depicts the average of individual samples analyzed in triplicates. Bottom: linear regression analyses of percent methylation at variable sites in AKR7A2 versus cardiac AKR7A2 protein expression in donors with and without DS. Each circle depicts the average of individual samples analyzed in triplicates.
