Table 3. Association of 6 SNPs With mAF >0.05 in Case and Control Populations and P<0.01 in the Discovery Cohort, in the Discovery and Replication Cohorts.
| SNP | Gene | Discovery Cohort P Value |
Replication Cohort P Value |
Entire Population P Value |
Bonferroni Corrected P Value (207 Comparisons) |
Odds Ratio (95% CI), Entire Population |
|---|---|---|---|---|---|---|
| rs11066320 | PTPN11 | 0.004 | 0.0002 | 2.9×10−6 | 6.1×10−4 | 1.34 (1.19–1.52) |
| rs9385353 | HEY2 | 0.001 | 0.7 | 0.08 | NS | 1.12 (0.99–1.27) |
| rs3095870 | NKX2.5 | 0.005 | 0.76 | 0.14 | NS | 1.10 (0.97–1.25) |
| rs723166 | FGF10 | 0.006 | 0.97 | 0.04 | NS | 1.16 (1.01–1.34) |
| rs121004 | CRKL | 0.01 | 0.71 | 0.08 | NS | 1.25 (0.97–1.60) |
| rs3729848 | GATA4 | 0.01 | 0.97 | 0.16 | NS | 1.14 (0.95–1.37) |
NS indicates not significant at P<0.05 after Bonferroni correction.