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GI50 values (μM) for test compounds in A375, RPMI7951, HeLa or Jurkat cells. The BRaf inhibitor PLX4032 was used as a control.
| A375 | RPMI7951 | HeLa | Jurkat | |
|---|---|---|---|---|
| SF-3-026 | 7.8 | 5.1 | 32 | >50 |
| SF-3-027 | 5.5 | 3.1 | 22 | >50 |
| SF-3-029 | 7.9 | 4.9 | 25 | >50 |
| SF-3-030 | 7.1 | 4.6 | 29 | >50 |
| PLX4032 | 0.060 | >10 | >10 | >10 |
