Figure 2.

Unsupervised hierarchical clustering of enriched pathways (gene sets) associated with pulmonary function. Rows representing enriched gene sets (n = 131) were grouped based on overlapping gene membership (columns). Gene sets with many shared genes clustered together and define functional modules (e.g. cell signaling, immunity and development). Columns represent gene membership profiles of enriched pathways and are colored according to association P-values of member genes. Note that for any given gene set, the majority of pathway-associated genes are not members and are displayed as black bars. For each clustered group (module), only representative pathways have been labeled. Complete list is available in Supplementary Material, Table S2.