Micrograph from mouse cremaster (A, shown maximally dilated with acetylcholine) and hamster cheek pouch (B, shown with normal resting tone; C, illustrating controlled drug exposure via micropipette delivery with the arteriole depicted by dotted lines). TA, terminal arteriole, and AA, arcade arteriole. Typical configurations for micropipette administered drug exposure are illustrated. The micropipette was placed so that the contents passed over the arterioles of interest and then washed away in the flowing tissue bath. C illustrates exposure at 15 seconds. scale bar = 10 μm.