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. Author manuscript; available in PMC: 2015 Nov 13.
Published in final edited form as: Nanotoxicology. 2013 Sep 30;8(8):867–875. doi: 10.3109/17435390.2013.837209

Figure 4.

Figure 4

Diameter changes (mean±SEM) with 30s continuous exposure to micropipette applied acetylcholine (panel A, 10−4 mol/L) or adenosine (panel B, 10−4 mol/L) before (pre) and 15–30 minutes after (post) nanotube exposure to the highest concentration of 50 μg/ml Fe-SWCNT or Gd-SWCNT (the concentration in the micropipette; kindly refer to the Methods for calculation of the exposure dose per arteriole). [Same animals as for Figure 3 so that paired comparisons could be made.] *post differs from pre, p<0.05. Agg = aggregated; non-Agg = non-aggregated. The data for the Gd-SWCNTs and Fe-SWCNTs are pooled together; there was no statistical difference in the data between these formulations (Gd- vs. Fe-SWCNT).