Table 1. Age-related response to Influenza A, Ag-sensitization, Ag-induced AHR and inflammation.
GROUP | MORBIDITY | OVA-IgE | BALF EOSINOPHILS | BALF NEUTROPHILS | AHR |
---|---|---|---|---|---|
Young OVA | NC | + | + + | + | + |
Young AI/OVA | + | + | + | + + | + + + |
Aged OVA | + + | + + | + + + | + + | + |
Aged AI/OVA | + + + | + + + | + + + | + + | + |
Determined by sickness score and weight loss
Ag, antigen; AHR, airway hyperresponsiveness; OVA, ovalbumin; BALF, bronchoalveolar fluid; AI, acute infection; NC, no change.