Table 2.
Treatment-related toxicity
| Grade 1 | Grade 2 | Grade 3 | Total | |
|---|---|---|---|---|
| Hematological toxicity, n (%) | ||||
| Anemia | 1 (3) | 0 (0) | 0 (0) | 1 (3) |
| Thrombocytopenia | 1 (3) | 0 (0) | 0 (0) | 1 (3) |
| Gastrointestinal toxicity (%) | ||||
| Diarrhea | 4 (14) | 0 (0) | 0 (0) | 4 (14) |
| Nausea | 0 (0) | 1 (3) | 0 (0) | 1 (3) |
| Vomiting | 0 (0) | 1 (3) | 0 (0) | 1 (3) |
| Bloating | 1 (3) | 0 (0) | 0 (0) | 1 (3) |
| Cholecystitis | 0 (0) | 0 (0) | 1 (3) | 1 (3) |
| Mucositis | 1 (3) | 0 (0) | 0 (0) | 0 (0) |
| Abdominal pain | ||||
| Cardiovascular toxicity (%) | ||||
| QT prolongation | 1 (3) | 0 (0) | 0 (0) | 1 (3) |
| Skin toxicity (%) | ||||
| Rash | 2 (7) | 0 (0) | 0 (0) | 2 (7) |
| Metabolism disorders (%) | ||||
| Hyperglycemia | 9 (32) | 9 (32) | 4 (14) | 22 (79) |
| Hypoglycemiaa | 1 (3) | 0 (0) | 0 (0) | 1 (3) |
| Miscellaneous | ||||
| Fatigue | 2 (7) | 0 (0) | 0 (0) | 2 (7) |
| Myalgia | 2 (7) | 0 (0) | 0 (0) | 2 (7) |
| Hypertransaminasemia | 1 (3) | 0 (0) | 0 (0) | 1 (3) |
| Elevated alkaline phosphatase | 1 (3) | 0 (0) | 0 (0) | 1 (3) |
a
Hypoglycemia that occurred during an episode of bowel obstruction in an insulin-treated patient.