Fig. 1.

(A) BCoS Complex Figure Copy task. Following the instruction, ““I will show you a figure. Please copy the figure the best you can”, the complex figure drawing is presented to the patient in the top half of an A4 page. Each patient is given a maximum of 5 min to complete the task. In the original task (Humphreys et al., 2012) performance is scored based on the presence (1 point each), shape/proportion (1 point each) and placement (1 point each) of 5 left elements (diagonal end/3 bars, rectangle, horizontal bar, double oblique bars/parallel and circle), 5 right elements (diagonal end/1 curved line, rectangle, horizontal bar, double oblique/triangle shape and double dot) and 5 middle elements (arrow, right curve, left curve, middle cross and main diagonal line). In addition, the presence and shape/proportion of the middle square is assigned 2 points, thus giving the maximum achievable score of 47 points for the completed task. (B) Lesion distribution. Lesion overlap map representing the spatial distribution of lesions among all 248 patients included in the current study. Lesion maps from individual patients were reconstructed using automated toolbox for lesion analyses based on CT scans (Gillebert et al., 2014); see Materials and Methods section for details. The lesion overlap map is shown for nine axial slices in standard MNI space with given MNI Z-coordinates of the presented axial sections. The colour bar shows the number of patients with a lesion within particular voxel. (C) Percentage of patients with disconnection in association, commissural and projection white matter pathways within the left and right hemisphere.