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. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: J Thromb Haemost. 2014 Oct 31;12(12):1993–2001. doi: 10.1111/jth.12742

Restricted cubic spline modeling of C-reactive protein (CRP) and serum albumin with VTE. Restricted cubic spline functions were analyzed with knots located at quartiles of the population distribution for (A) CRP (25^th %: 0.94 mg/L; 50^th %: 2.17 mg/L; and 75^th %: 4.96 mg/L) with the reference category set at 1 mg/L; and, (B) serum albumin (25^th %: 4.0 g/dL; 50^th %: 4.2 g/dL; and 75^th % 4.4 g/dL) with the reference category set at 4.0 g/dL. Solid lines represent hazard ratios; dashed lines represent 95% confidence intervals. Analyses were adjusted for age, sex, race, region, and race*region interaction.

Restricted cubic spline modeling of C-reactive protein (CRP) and serum albumin with VTE. Restricted cubic spline functions were analyzed with knots located at quartiles of the population distribution for (A) CRP (25^th %: 0.94 mg/L; 50^th %: 2.17 mg/L; and 75^th %: 4.96 mg/L) with the reference category set at 1 mg/L; and, (B) serum albumin (25^th %: 4.0 g/dL; 50^th %: 4.2 g/dL; and 75^th % 4.4 g/dL) with the reference category set at 4.0 g/dL. Solid lines represent hazard ratios; dashed lines represent 95% confidence intervals. Analyses were adjusted for age, sex, race, region, and race*region interaction.