Table 3.
Cox proportional hazards models of biomarkers of inflammation with incident VTE (per SD increment)
Biomarker | Model 1(HR, 95% CI) | Model 2(HR, 95% CI) | Model 3(HR, 95% CI) |
---|---|---|---|
lnCRP (per 1.18) | 1.34 (1.18, 1.52) | 1.26 (1.10, 1.44) | 1.25 (1.09, 1.43) |
Albumin (per 0.33 g/dL) | 1.29 (1.09, 1.51) | 1.24 (1.05, 1.47) | 1.25 (1.06, 1.48) |
White Cell Count(per 2.8 ×109 cells/L) | 1.00 (0.87, 1.17) | 0.98 (0.79, 1.23) | 1.00 (0.83, 1.21) |
Platelet Count(per 69.0 ×109 cells/L) | 1.03 (0.87, 1.22) | 1.07 (0.90, 1.26) | 1.05 (0.88, 1.25) |
Biomarkers were modeled per standard deviation (SD) (shown in parentheses) higher for lnCRP, white cell count, and platelet count, and per SD lower serum albumin.
Model 1: Age, sex, race, region, race*region interaction.
Model 2: Model 1 + body mass index, smoking, hypertension.
Model 3: Model 2 + diabetes, and history of coronary heart disease or stroke.