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. 2015 Nov 13;10(11):e0142939. doi: 10.1371/journal.pone.0142939

Fig 3. 5-Azacytidine-induced differentiation.

Fig 3

A: Densitometry showing significant reduction in O-GlcNAcylation at day 7 upon initiating differentiation stimuli in CSCs. B: Conversely, an enhanced O-GlcNAc status influences commitment to a cardiogenic lineage in terms of significantly reduced mRNA expression of an early cardiac transcription factor Nkx2.5. C: During this time, O-GlcNAc levels were maintained at an elevated degree as depicted in the immunoblot. D: Densitometric quantification showing significantly elevated O-GlcNAcylation due to TMG. Individual data points are plotted and the horizontal line represents the mean, n>/ = 3/group, *p < 0.05 vs day 0/-TMG.