Table 2.
Neuropsychological, behavioral, exercise and fMRI task outcome data for both participant groups.
| MCI(n=17) | Controls(n=18) | |||||
|---|---|---|---|---|---|---|
| Variables | Pre-mean (SD) | Post-mean (SD) | Pre-mean (SD) | Post-mean (SD) | Time main effect p | Group x Time effect p |
| Neuropsychological Testing | ||||||
| AVLT Trial 1 | 3.9 (2.1)a | 5.0 (2.1)a | 5.4(1.9) | 6.3 (1.5) | .006 | .80 |
| AVLT Trials 1–5 | 34.9 (13.8) 37.1 (15.5) | 49.3(9.4) | 52.4 (7.9) | .06 | .73 | |
| AVLT IR | 5.1 (4.0) | 5.9 (4.4) | 11.2(2.3) | 11.2 (1.7) | .29 | .29 |
| AVLT DR | 5.5 (4.4) | 5.0 (4.6) | 10.4(3.2) | 11.3 (2.0) | .68 | .23 |
| Clock Drawing Test | 2.5 (1.2) | 2.2 (0.8) | 1.4(0.8) | 1.2 (0.7) | .06 | .49 |
| Depression Symptoms and Physical Function | ||||||
| GDS | 6.3 (3.6) | 6.1 (3.3) | 3.4(2.8) | 3.3 (3.6) | .84 | .94 |
| Lawton ADL | 4.7 (0.5) | 4.5 (0.9) | 4.7(0.5) | 4.7 (0.5) | .23 | .45 |
| Exercise Testing | ||||||
| VO2peak (ml/kg/min) | 19.1 (4.1) | 21.5 (3.4) | 20.1 (5.0) | 21.2 (4.1) | .004 | .24 |
| fMRI Task Performance | ||||||
| % Correct Famous | 80.2 (16.4) | 77.8 (14.0) | 87.1(15.8) | 83.6 (18.9) | .16 | .78 |
| % Correct Non-Famous | 83.2 (18.6) | 84.1 (16.6) | 93.7(6.8) | 94.3 (5.7) | .72 | .93 |
| RT Famous (ms) | 1398 (319) | 1340 (308) | 1335(362) | 1361 (259) | .74 | .41 |
| RT Non-Famous (ms) | 1691 (390) | 1669 (481) | 1574(332) | 1715 (295) | .24 | .12 |
Note: Significant difference between common superscript a, p < .01; ADL = activities of daily living; AVLT = Rey Auditory Verbal Learning Test; DR = delayed recall; GDS = Geriatric Depression Scale; IR = immediate recall; RT = reaction time; VO2peak = peak rate of oxygen consumption. fMRI task performance did not change over time, and the groups differed only in %Correct Non-famous (Group main effect, p < .05).