FIG. 4.

Pubic symphysis elongation in late pregnant females with mutations of Rxfp1 gene. Shown are representative images of dissected pubic symphyses with arrows showing their lengths. Significant relaxation of the pubic symphysis is present in late pregnant versus nonpregnant wild-type females. There was no dilation of the pubic symphysis in Rxfp1^ko/ko females and a partial dilation in Rxfp1^fl/ko, Tagln-cre females with conditional gene deletion. A total of 6–10 mice of each genotype were analyzed (Table 1). Bar = 5 mm.