Table 1. Kinetics parameters of eukaryotic, bacterial and archaeal MVKs.

Species	Km MA (μM)	Km ATP (μM)	Vmax (μmol min-1 mg-1)	Kcat (s-1)	Ki GPP (μM)	Ki FPP (μM)	Reference
A. aegypti	90	140	33	10.1	0.55	0.44	This Work
S. bullata	620	4700	ND	ND	ND	ND	[22]
R. norvergicus	35	950	39	21.9	ND	2.50	[41]
H. sapiens	150	440	14	ND	0.11	0.10	[13]
S. pneumonia	236	372	ND	11.0	NI	NI	[18]
S. aureus	41	339	12	ND	ND	>10	[42]
M. jannaschii	106	1180	50	28.5	>10	>10	[41]
M. mazei	68	464	ND	4.3	NI	NI	[18]

ND: Not Determined; NI: not inhibitory.