Skip to main content
. 2015 Nov 13;10(11):e0142161. doi: 10.1371/journal.pone.0142161

Table 1. Apoptosis induced by Jo2.

%AnnexinV/CD44hi/CD8+ IgG Jo2
WT Day 0 p.i. 33.74±2.16 34.14±2.45
KO Day 0 p.i. 37.54±3.74 38.77±3.56
WT Day 2 p.i. 38.37±1.58 48.35±1.83*
KO Day 2 p.i. 51.82±0.74** 60.17±1.26* , **
%AnnexinV/CD44hi/CD4+ IgG Jo2
WT Day 0 p.i. 52.46±2.31 63.7±1.28*
KO Day 0 p.i. 57.26±2.46 67.43±1.33*, **
WT Day 2 p.i. 60.37±1.39 69.27±0.84*
KO Day 2 p.i. 68.37±0.8** 74.45±1.05* , **

This table represents the percentage of AnnexinV+ WT and KO CD44hiCD8 and CD44hiCD4 cells after culturing the splenocytes of naïve (day 0) or day 2 p.i. chimaeric mice in the presence of either IgG control or the Fas agonist Jo2 for 16 hours. (n = 4 mice per timepoint, ± = SEM).

*p ≤ 0.05 between IgG and Jo2 conditions

**p ≤ 0.05 between WT and KO under the IgG or Jo2 condition