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. Author manuscript; available in PMC: 2015 Nov 13.
Published in final edited form as: Gastroenterology. 2009 Sep 2;138(1):197–209. doi: 10.1053/j.gastro.2009.08.054

Figure 1.

Figure 1

Effect of HIV PIs on paracellular permeability in IEC cells. (AC) IEC-6 cells were treated with individual HIV PIs (0–25 μmol/L) for 24 hours. (D) IEC-cdx2L1 cells were cultured on the filter in Dulbecco’s modified Eagle medium containing 4 mmol/L isopropyl- β - D-thiogalac-topyranoside for 16 days to induce differentiation and treated with individual HIV PIs(25 μmol/L) for 24 hours. The paracellular permeability was measured as described in Materials and Methods. Values are mean ± SD of 3 independent experiments and analyzed using one-way analysis of variance. **P < .01, ***P < .001.