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This study captured two mechanisms by which a longer versus shorter screening interval might lead to breast cancers with less-favorable characteristics: (1) more time for tumor growth between the index screening mammogram m′ and the previous screen m; and (2) more time for a tumor to become symptomatic and clinically detected after a negative screening mammogram m′. BrCa indicates breast cancer; follow-up, follow-up period for cancer ascertainment.
