Table 1.

Basic Measurements for the 22 C57Bl/6 Pkd1 ^RC/RC Mice

Measurement	9 Months Old		12 Months Old		15 Months Old
	Female	Male	Female	Male	Female	Male
Body weight, g	23.8 ± 0.4	25.8 ± 1.8	24.1 ± 1.5	29.5 ± 2.0	23.9 ± 1.5	28.5 ± 2.0
Kidney weight, g	0.9 ± 0.2	0.6 ± 0.1	1.0 ± 0.2	0.7 ± 0.1	1.0 ± 0.3	0.7 ± 0.1
KW/BW, %	3.8 ± 0.7	2.2 ± 0.2	4.0 ± 0.9	2.2 ± 0.2	4.3 ± 1.0	2.5 ± 0.3
BUN, mg/dl	45 ± 19	18 ± 3	74 ± 36	21 ± 4	93 ± 28	28 ± 3
H&E cystic index, %	22 ± 5	8 ± 3	42 ± 12	11 ± 5	42 ± 11	16 ± 9
PSR fibrotic index, %	17 ± 6	2 ± 1	16 ± 7	5 ± 1	16 ± 6	6 ± 8
TRI fibrotic index, %	18 ± 6	2 ± 1	14 ± 5	8 ± 3	18 ± 4	9 ± 10

Data are presented as the mean ± standard deviation. Cystic index was measured in H&E stained histological sections, and fibrotic index was measured by both picrosirius red and Masson's trichrome stained histological sections.

Abbreviations: BUN, blood urea nitrogen; H&E, hematoxylin and eosin; KW/BW, kidney weight/body weight; PSR, picrosirius red; TRI, Masson's trichrome.