Table 1.
Descriptive Characteristics of 15 Randomized Controlled Trials Evaluated Integrated Interventions for Persons Living with HIV (PLWH)
| First Author, Year [Citation Number], Study Years | Targeted Behaviors | HIV-positive Subpopulation (Baseline Sample Size) | Comparison Group, Power Analysis to Estimate Sample Size (Yes/No) | Intervention Name (# of sessions; total hours), Intervention Level, Tailored/not Tailored to Individual, Deliverer, Service/Care Setting (vs. Other) |
|---|---|---|---|---|
| Holstad et al., 2011 [35], 2005-2008 | • Risk reduction • Medication adherence |
Women who were prescribed antiretroviral medicine (203) | Attention control, Power analysis: No | Group Motivational Interviewing (8;16) Group format, Tailored, delivered by health care provider or counselor, in service/care setting |
| Kalichman et al., 2011 [41], 2005-2009 | • Risk reduction • Medication adherence |
None (436) | Attention control, Power analysis: Yes | In the Mix (7;12) One-on-one & group format, Not Tailored, delivered by trained Facilitator, in service/care setting |
| Konkle-Parker et al., 2012 [27], 2005-2006 | • HIV care engagement • Medication adherence |
Clinic patients starting or restarting antiretroviral medicine (56) | Standard of care, Power analysis: No | Pilot study of an HIV medication adherence intervention (8;3) One-on-one delivery, Tailored, delivered by trained facilitator, in service/care setting |
| Konkle-Parker et al., 2014 [28], 2009-2011 | • HIV care engagement • Medication adherence |
Clinic patients with medication or visit adherence problems (100) | Standard of care, Power analysis: No | CLIMB: Cornerstones of Life: Information, Motivation, Behavioral Skills (8;4) One-on-one delivery, Tailored, delivered by trained facilitator, in service/care setting |
| Kurth et al., 2014 [29], 2006-2007 | • Risk reduction • Medication adherence |
Clinic patients who were prescribed antiretroviral medicine (240) | Standard of care, Power analysis: Yes | CARE+: Computer Assessment & Rx Education for HIV-positive people (4;2) One-on-one delivery, Tailored, delivered by computer, in service/care Setting |
| MacGowan et al., 2014 [37], 2008-2009 | • Risk reduction • HIV care engagement • Medication adherence |
Inmates reentering the community (73) | HIV demand control, Power analysis: No | POST: Positive Transitions (6;9) One-on-one delivery, Not Tailored, Delivered by trained facilitator, in other setting (e.g., prison, community) |
| Margolin et al., 2003 [30], 1997-2001 | • Risk reduction • Medication adherence |
Clinic patients who were Injection drug users in methadone maintenance treatment (90) | HIV demand control, Power analysis: No | HHRP+: HIV+ Harm Reduction Program (48;minimum of 96) One-on-one and & group format, Not Tailored, delivered by health care provider or counselor, in service/care setting |
| Naar-King et al., 2006 [32], NR | • Risk reduction • Medication adherence |
Clinic patients who were adolescents aged 16-25 years (65) | Standard of care, Power analysis: No | Healthy Choices pilot Study (4;4) One-on-one delivery, Tailored, delivered by health care provider or counselor, in service/care setting |
| Naar-King et al., 2009 [31], 2005-2007 | • Risk reduction • Medication adherence |
Clinic patients who were adolescents aged 16-24 years with medication adherence, substance abuse or sexual risk problems (205) | Standard of care, Power analysis: No | Healthy Choices (4;6) One-on-one delivery, Tailored, delivered by health care provider or counselor, in service/care setting |
| Healthy Living Project Team, 2007 [40], 2000-2004 | • Risk reduction • Medication adherence |
Unprotected sex with HIV-negative or status unknown partners (936) | Waitlist, Power analysis: Yes | Healthy Living Project (15;22.5) One-on-one delivery, Not Tailored, delivered by trained facilitator, in service/care setting |
| Purcell et al., 2007 [34], 2001-2004 | • Risk reduction • HIV care engagement • Medication adherence |
Injection drug users (966) | HIV demand control, Power analysis: Yes | INSPIRE: Interventions for Seropositive Injectors – Research and Evaluation (10;20) Group format, Not Tailored, delivered by trained facilitator, in other setting (e.g., research facility) |
| Reznick et al., 2013 [38] NR | • Risk reduction • Medication adherence |
Inmates reentering the community (151) | HIV demand control, Power analysis: No | Ecosystems-based intervention (2-18;NR) One-on-one & group format, Tailored, delivered by health care provider or counselor, in other setting (e.g., prison, community) |
| Rotheram-Borus et al., 2004 [33], 1999-2003 | • Risk reduction • HIV care engagement • Medication adherence |
Young substance abusers aged 16 to 29 years (175) | Waitlist, Power analysis: No | CLEAR: Choosing Life: Empowerment, Actions, Results (18;27) One-on-one delivery, Not Tailored, Delivered by health care provider or counselor, in other setting (e.g., coffee shops, community, parks, residences) |
| Wolitski et al., 2010 [39], 2004-2007 | • Risk reduction • HIV care engagement • Medication adherence |
Homeless or at severe risk of homelessness (644) | HIV demand control, Power analysis: Yes | Housing Assistance & HIV Prevention (case management + 2 HIV sessions;1.25) One-on-one delivery, Not Tailored, Delivered by trained facilitator, in other setting (e.g., housing project) |
| Wyatt et al., 2004 [36], NR | • Risk reduction • Medication adherence |
Women with histories of childhood sexual abuse (147) | HIV demand control, Power analysis: No | Enhance Sexual Health Intervention (11;22) Group format, Not Tailored, delivered by trained facilitator, in other setting (e.g., research facility) |
NR=not reported