. Author manuscript; available in PMC: 2017 Jan 1.

Published in final edited form as: Diabet Med. 2015 May 29;33(1):32–38. doi: 10.1111/dme.12799

Table 3.

Association between history of gestational diabetes and diabetes by randomization arm, before and after adjustment for baseline biomarker levels

	Hazard ratio (95% CI)
	Intensive lifestyle change	Metformin	Placebo
Unadjusted association between history of gestational diabetes and diabetes	1.53 (0.95, 2.48)	1.00 (0.62, 1.61)	1.65 (1.16, 2.34)
Adjusted for baseline log CRP, age (years), race (white vs. non- white), and weight (kg)	1.42 (0.84, 2.40)	1.15 (0.69, 1.93)	1.79 (1.21, 2.63)
Adjusted for baseline fibrinogen, age (years), race (white vs. non- white), and weight (kg)	1.43 (0.85, 2.41)	1.12 (0.67, 1.88)	1.71 (1.17, 2.52)
Adjusted for baseline adiponectin, age (years), race (white vs. non- white), and weight (kg)	1.32 (0.78, 2.25)	1.06 (0.62, 1.82)	1.81 (1.23, 2.66)
Adjusted for baseline tissue plasminogen-activator antigen, age (years), race (white vs. non- white), and weight (kg)	1.46 (0.87, 2.47)	1.14 (0.68, 1.90)	1.74 (1.19, 2.56)

CRP, C-reactive protein.

Referent group is women without history of gestational diabetes.