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. 2015 Nov 6;10:6943–6953. doi: 10.2147/IJN.S82778

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© 2015 Zhang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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The charaterization of the I-doped CDs biocompatibility.

Notes: (A) Effect of I-doped CDs on the viability of 4T1 and A549 cells using the MTS assay. (B) Laser scanning confocal microscopy images of 4T1 and A549 cells stained with potassium iodide and I-doped CDs (scale bars =50 μm). (C) Hemolytical activity of the I-doped CDs at different concentrations (50, 100, 200, 300, and 400 μg/mL). PBS and water were used as negative and positive control, respectively.

Abbreviations: OD, optical density; I-doped CDs, iodine-doped carbon dots; PBS, phosphate buffer saline; MTS, 3-(4,5-dimethyl-thiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium.