Figure 2.

Oral B401 treatment prolongs life and maintains body weight of R6/2 (HD) mice.

Notes: (A) Survival duration of R6/2 mice given the oral B401 treatment was longer than those given the sham treatment. (B) Averaged body weight of R6/2 mice given the oral B401 treatment was significantly higher when compared with those given the sham treatment from 10 weeks of age and thereafter. The number of R6/2 mice under oral B401 and sham treatments were 22 and 20, respectively. Values are mean ± SEM (*P<0.05, **P<0.01, one-way ANOVA followed by a Student–Newman–Keuls multiple comparison posttest).

Abbreviations: HD, Huntington’s disease; ANOVA, analysis of variance; SEM, standard error of the mean.