Table 4.
Multivariate analysis of risk factors associated with mortality and post-hepatectomy liver failure (survivors without liver failure represent the reference group)
| Factor | Odds ratio (95% CI) | P-value |
|---|---|---|
| Risk factors associated with mortality | ||
| EBL (OR associated with each 100-ml increase) | 1.08 (1.04–1.11) | <0.001 |
| Primary versus metastatic disease | 2.66 (1.43–5.00) | 0.002 |
| Age (OR associated with 1-year increase) | 1.04 (1.01–1.07) | 0.005 |
| Preop albumin (OR associated with 0.1-mg/dl decrease) | 1.11 (1.05–1.18) | 0.001 |
| Creatinine increase (PoD 1 > DoS and phosphate fails to decrease by 20% from DoS to PoD 1 | 2.53 (1.36–4.71) | 0.003 |
| Risk factors associated with PHLF | ||
| Primary versus metastatic disease | 1.19 (0.49–2.72) | 0.69 |
| Preoperative cholestasis (total bilirubin >1.5) | 7.08 (2.68–17.8) | <0.001 |
| Creatinine increase (PoD 1 > DoS and phosphate fails to decrease by 20% from DoS to PoD 1 | 3.89 (1.85–8.37) | <0.001 |
95% CI, 95% confidence interval; DoS, day of surgery; EBL, estimated blood loss; OR, odds ratio; PHLF, post-hepatectomy liver failure; PoD, postoperative day.