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. 2015 Sep 28;7(11):1426–1449. doi: 10.15252/emmm.201404976

Figure 11. YAP expression in normal, HPV16 E6, and HPV16 E6/E7-induced cancerous cervical tissues in a transgenic mouse model, and HPV16-containing human foreskin keratinocyte raft cultures.

Figure 11

  • A–F Representative images showing expression of YAP (in red) in wild-type mouse cervical tissues (n = 5) (A), HPV16 E6-induced (C) and HPV16 E6/E7-induced (E) mouse cervical tumor tissue (n = 4 each). Scale bars for (A), (C), and (E): 100 μm. High-resolution images showing the expression and cellular location of YAP in normal cervical tissues (B), HPV16 E6-induced (D) and HPV16 E6/E7-induced (F) mouse cervical tumor tissue. Scale bars for (B), (D), and (F): 25 μm.
  • G, H Representative images showing expression of YAP (in red) in normal (G) and HPV16-containing human foreskin keratinocyte raft cultures (n = 5 each) (H). Scale bars: 100 μm.
  • I, J High-resolution images showing the expression and cellular location of YAP in normal (I) and HPV16-containing human foreskin keratinocytes raft cultures (J). Scale bars: 20 μm.