Table 3.

Multivariate analysis of key parameters and clinical outcomes

Parameter	Hazard ratio (DFS)	p value (DFS)	Hazard ratio (OS)	p value (OS)
Stagea		0.58b		0.21b
III	1.3	0.32	1.4	0.3
IV	1.3	0.35	0.87	0.75
III versus IV	1.0	0.91	0.6	0.12
Gender	0.76	0.12	0.66	0.07
Age	1.03	0.90	1.26	0.39
Immune response	0.93	0.69	1.05	0.83

^aThe reference group is patients with stage II melanoma unless otherwise stated

^bCumulative p value for all stages