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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Neurochem. 2015 Jun 18;135(6):1203–1217. doi: 10.1111/jnc.13169

Figure 3. Liraglutide treatment protects neural cells from glutamate-induced cell death.

Figure 3

SH-SY5Y#9 cells were pretreated with a series concentrations (0, 10−9 , 10−8, 10−7, 10−6 M) of liraglutide for 1h, then challenged with either 75 mM (A) or 100 mM glutamate (B) for 24h before performing an MTS assay to assess cell viabilities. In (A), cell viability of liraglutide (1×10−6 M) + glutamate challenge was significantly greater than + glutamate challenge alone. In (B), cell viability following glutamate challenge alone was significantly reduced compared to all groups with the exception of liraglutide (1×10−9 M) (**P <0.01; ***P < 0.001).