Table 4.
Comparison between healthy patients and patients with CF with or without CFLD. ANOVA test and post hoc (Bonferroni) for SWV in right hepatic lobe (RHL), left hepatic lobe (LHL), and spleen. Student's t-test for the main variables, BMI and FEV1.
| Group I | Group II | Group III | F/t | P | Post hoc comparison | |
|---|---|---|---|---|---|---|
| Healthy children | Patients with CF without liver disease | Patients with CFLD | ||||
| N = 60 | N = 49 | N = 23 | ||||
| Mean (SD) | Mean (SD) | Mean (SD) | ||||
| RHL | 1.19 (0.13) | 1.18 (0.18) | 1.31 (0.16) | 6.023 | 0.003 | Group I–group III |
| Group II-group III | ||||||
| LHL | 1.27 (0.19) | 1.27 (0.24) | 1.34 (0.30) | 0.930 | 0.397 | |
| Spleen | 2.16 (0.35) | 2.51 (0.30) | 2.51 (0.31) | 18.154 | <0.0001 | Group I-group II |
| Group I–group III | ||||||
| FEV1 | 87.85 (15.21) | 91.05 (16.17) | −0.777 | 0.440 | ||
| BMI | 17.67 (2.92) | 17.30 (3.19) | 0.48 | 0.633 | ||
| GOT | 33.94 (13.03) | 64.17 (114.47) | −1.82 | 0.073 | ||
| GPT | 27.5 (14.08) | 54.13 (101.43) | −1.79 | 0.077 | ||
| GGT | 15.5 (14.56) | 79.79 (272.87) | −1.64 | 0.106 | ||
| AP | 187.89 (61.79) | 189.65 (73.82) | −0.105 | 0.917 | ||
| TB | 0.63 (0.54) | 0.31 (0.16) | 1.229 | 0.223 | ||
| Glu | 93.79 (10.37) | 95.26 (16.75) | −0.454 | 0.651 | ||
| Albu | 4.03 (0.30) | 3.97 (0.27) | 0.943 | 0.349 | ||
| Colin | 9370.23 (2051.30) | 8493.68 (1398.98) | 1.693 | 0.096 |
RHL = right hepatic lobe; LHL = left hepatic lobe; FEV1 = pulmonary function; BMI = body mass index; GOT = aspartate-aminotransferase; GPT = alanine-aminotransferase; GGT = γ-glutamyl-transpeptidase; AP = alkaline phosphatase; TB = total bilirubin; Glu = glucose; Albu = albumin; Colin = cholinesterase.