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A summary of copy number variations during tumor progression.
| Early phase (common mutations) |
Middle phase (shared mutations) |
Late phase (unique mutations) |
|||
|---|---|---|---|---|---|
| Gain/amplification | Deletion | Gain/amplification | Deletion | Gain/amplification | Deletion |
| EGFR | CDKN2A/B | chr7 | chr10 | GLUT9 | |
| CDK6 | PTEN | 19p12/13 | (PTEN) | PDGFRA | |
| MET | PDGFRA | ||||
The patterns in genetic variance over time described in this table were obtained from the study by Sottoriva et al. (10).
