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Different metabolite enzyme activity ratios in rat skeletal muscle after the injection of 40 mmol l−1 hyperpolarized [1-13C]lactate. (A) Metabolite ratios calculated from time-averaged (0–2 min) spectra. (B) Metabolite production rates (r). (C) Time to half-maximum (τ). Asterisk indicates statistically significant difference between pre-/post-DCA measurements (*P<0.05).
