Table 2. Comparison of the clinical characteristics of the two clades of children with EV-D68.

Patient characteristic	EV-D68 N (%)				Clade N (%)
	Total	Single detection	Co-detection	Pvalue	Clade A	Clade B	Pvalue
Number	19	8	11		4	15
Gender (male)	10 (53)	3 (38)	7 (64)	0.370	2 (50)	8 (53)	1.00
Median age (months)	32 (1–128)	41.5 (16–128)	16 (1–83)	0.091	4.5 (1–7)	43 (16–128)	0.001
Median (days)
Duration of hospitalization	6 (3–11)	4.5 (3–7)	6 (3–11)	0.152	8.5 (5–11)	5 (3–7)	0.027
Past history
A past history of asthma	7 (37)	3 (38)	4 (36)	1.0	0	7 (47)	0.245
A past history of recurrent wheezing	13 (68)	7 (88)	6 (55)	0.177	1 (25)	12 (80)	0.071
Clinical symptoms
Cough	19 (100)	8 (100)	11 (100)	/	4 (100)	15 (100)	/
Fever	5 (26)	2 (25)	3 (27)	1.0	1 (25)	4 (27)	1.0
Wheezing	17 (89)	8 (100)	9 (82)	0.485	4 (100)	13 (87)	1.0
Diagnosis
A discharge diagnosis of asthma	13 (68)	8 (100)	5 (45)	0.018	0	13 (87)	0.004
Acute asthma exacerbations	11 (58)	7 (88)	4 (36)	0.059	0	11 (73)	0.018