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. 2015 Nov 16;5:16605. doi: 10.1038/srep16605

Figure 1. Natural and semi-synthetic GPBAR1 and FXR agonists.

Figure 1

CDCA and TLCA, endogenous activators of FXR and GPBAR1, respectively. INT-767 and compound 2, potent dual FXR/GPBAR1 agonists and EUDCOH, a selective GPBAR1 agonist.