Table 2. Parasitemia of P. chabaudi Infected Mice Treated with a Single Intraperitoneal Dose of 1 or 3.
| mean parasitemia ± SEM (%) |
||||
|---|---|---|---|---|
| cmpd | dose (mg/kg) | day 4a | day 7 | day 13 |
| vehicle | 4.6 ± 0.5 | 34 ± 2.3 | b | |
| 1 | 10 | 4.8 ± 0.5 | 0.02 ± 0.01 | 0 |
| 3 | 8 | 4.8 ± 0.4 | 33 ± 1.5 | b |
| 3 | 16.5 | 4.5 ± 1.1 | 0.7 ± 0.2 | 0.65 ± 0.65 |
| 3 | 50 | 5.4 ± 0.6 | 0 | 0 |
Day postinoculation; animals dosed on day 4.
Animals sacrificed on day 8 due to poor health, as dictated by study protocol.