Table 3. Noncompartmental Pharmacokinetic Parameters for 3 in Plasma Following i.p. Administration of 50 mg/kg in Uninfected or Infected Mice.

parameter	units	uninfected	infected
terminal t1/2	h	8.41	8.60
tmax	h	1.00	2.00
Cmax	ng/mL	3620	1570
AUCinf	h·ng/mL	34100	13600
CL/F	mL/h/kg	1470	3670
dose/Cmax	L/kg	13.8	31.8
Vz/F	L/kg	17.8	45.5
MRTlast	h	6.93	6.43
MRTinf	h	11.0	10.6