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Codon optimization of human MR. (A). The histograms show the percentage of sequence codons, which fall into a certain quality class. The quality value of the most often used codon for a given amino acid in the desired expression system is set to 100, the remaining codons are scaled accordingly [52]. (B). The plots show the quality of the used codon at the indicated codon position. (C). The plots show the GC content in a 40 bp window centered at the indicated nucleotide position.
