TABLE 1.

Data collection and refinement statistics

Parameters	Value(s) for indicated NP
	ERVEV NP(1–482)	ERVEV NPhead	KUPV NP	HAZV NP
Data collection statistics
Cell parameters
a (Å)	49.90	46.08	73.98	67.40
b (Å)	67.90	104.29	73.98	72.17
c (Å)	154.08	70.54	423.98	453.67
α, β, γ (°)	90.0, 93.6, 90.0	90.0, 92.4, 90.0	90.0, 90.0, 90.0	90.0, 90.0, 90.0
Space group	P21	P21	P41212	P212121
Wavelength used (Å)	1.0000	1.0000	1.0000	1.0000
Resolution (Å)a	50.00–2.35 (2.39–2.35)	50.00–1.80 (1.83–1. 80)	50.00–2.60 (2.64–2.60)	50.00–2.90 (2.95–2.90)
No. of all reflectionsa	184,478 (50,568)	227,184 (11,363)	421,320 (17,390)	256,728 (17,338)
No. of unique reflectionsa	42,902 (2,134)	61,401 (3,071)	37,285 (1,739)	42,788 (2,442)
Completeness (%)	99.3 (100.0)	99.6 (100.0)	98.5 (93.9)	84.7 (100)
Average I/σ(I)	9.1 (3.9)	14.7 (3.6)	20.9 (4.3)	11.1 (4.0)
Rmergeb (%)	12.6 (39.9)	7.7 (35.1)	9.2 (42.2)	11.6 (35.2)
Refinement statistics
No. of reflections used [σ(F) > 0]	42,875	61,367	37,162	42,731
Rworkc (%)	17.4	16.8	21.2	20.7
Rfreed (%)	24.8	20.2	28.0	28.7
RMSD
Bond distance (Å)	0.008	0.006	0.009	0.009
Bond angle (°)	1.109	0.992	1.150	0.922
Average B value (Å2):
For protein atoms	44.1	30.0	51.4	62.6
For ligand atoms	0	0	0	0
For solvent atoms	46.3	37.7	44.0	39.2
No. of:
Protein atoms	7,381	5,750	7,340	14,874
Ligand atoms	0	0	0	0
Solvent atoms	270	679	92	104
Ramachandran plot (%)
Favored regions	95.9	97.5	93.1	96.1
Allowed regions	3.9	2.4	6.5	3.9
Outlier regions	0.2	0.1	0.4	0

^aNumbers in parentheses are corresponding values for the highest-resolution shell.

^bR_merge = Σ_hΣ_l |I_ih − <I_h>|/Σ_hΣ_I <I_h>, where <I_h> is the mean of the observations I_ih of reflection h.

^cR_work = Σ(||F_p(obs)| − |F_p(calc)||)/Σ|F_p(obs)|.

^dR_free is an R factor for a preselected subset (5%) of reflections that was not included in the refinement.