Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Putative polyprotein cleavage sites of EPEV polyprotein
| Cleavage site | Protease | Amino acid sequence |
|---|---|---|
| VirC/AnchC | VSP | KKKRR/NGGTA |
| AnchC/prM | HS | MMIVC/YVNAR |
| Pr/M | Furin | HRHRR/RSPRS or RRSPR/SIAMP |
| M/E | HS | GPAYG/THCLT |
| E/NS1 | HS | TGVGA/DVGCS |
| NS1/NS2A | ? | SLVSA/GNGMV |
| NS2A/NS2B | VSP | WRKTR/SWPIS |
| NS2B/NS3 | VSP | RSKRR/AGILW |
| NS3/NS4A | VSP | AEGRR/NWTGL |
| NS4A/2K | VSP | EPGCQR/SAQDN |
| 2K/NS4B | HS | AGVAA/NELGW |
| NS4B/NS5 | VSP | KSFRR/GKAQA |
